A driver-state detection system and method with an accelerator pedal control function detects a driver's state and controlling an accelerator pedal to prevent an accident. The driver-state detection system with an accelerator pedal control function includes a driver-state detector detecting a driving state of a driver and determining whether the driver is carelessly driving a vehicle or not, a pedal controller receiving an operation signal from the driver-state detector, a vehicle state detector determining whether the vehicle is driven or stopped, based on ambient signals of the vehicle, an operation pedal installed to receive operation signals from the pedal controller and the vehicle state detector, and a vibration generator installed on the operation pedal and provided to generate or cancel a vibration of a motor.