A multi-use therapeutic pillow for the head includes a cushioned frame having a central cavity that extends therethrough. A cushioned transverse member, operably coupled to the cushioned frame at its opposite ends, divides the central cavity into a lower cavity and an upper cavity. The lower cavity is larger than the upper cavity. In use, the multi-use therapeutic pillow is configured to protect and/or avoid contact with a sensitive anatomical structure, such as, the eyes, ears, nose, or mouth, while providing adequate support for the head.