A surgical instrument includes an end effector having an actuator effecting a surgical procedure when actuated, an electric motor operating the actuator, and a power supply actuating the actuator when power is supplied to the motor. The power supply has a battery cell with a given rated power for an operating period of over 15 seconds and for a total aggregate operating time of over 300 seconds. The motor and power supply are configured to utilize the battery cell at a power greater than the given rated power. The motor characteristics are selected to utilize the battery cell for periods of operation of less than 16 seconds and for a total aggregate operating time of less than 300 seconds. A one-handed handle contains all of the power supply, at least part of an anvil control assembly, and at least part of an electrically-powered stapler/cutter control assembly.