Invention Grant
- Patent Title: Pharmaceutical composition to protect an animal against a disorder arising from an infection with a bacterium that belongs to the group of nocardioform actinomycetes
- Patent Title (中): 用于保护动物免受由属于诺卡氏菌放线菌组的细菌感染引起的病症的药物组合物
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Application No.: US13144042Application Date: 2010-01-11
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Publication No.: US08574565B2Publication Date: 2013-11-05
- Inventor: Antonius Arnoldus Christiaan Jacobs , Robert Van Der Geize , Lubbert Dijkhuizen
- Applicant: Antonius Arnoldus Christiaan Jacobs , Robert Van Der Geize , Lubbert Dijkhuizen
- Applicant Address: NL Boxmeer
- Assignee: Intervet International B.V.
- Current Assignee: Intervet International B.V.
- Current Assignee Address: NL Boxmeer
- Priority: EP09150379 20090112
- International Application: PCT/EP2010/050196 WO 20100111
- International Announcement: WO2010/079224 WO 20100715
- Main IPC: A61K35/74
- IPC: A61K35/74 ; C12N1/20 ; A61P31/04
Abstract:
The invention pertains to a pharmaceutical composition to protect an animal against a disorder arising from an infection with a bacterium that belongs to the group of nocardioform actinomycetes having the ability to survive within macrophages of the animal, comprising live bacteria of a nocardioform actinomycetes species, the live bacteria being attenuated by inactivation of a gene that encodes a protein involved in methylhexahydroindanedione propionate degradation, and a pharmaceutically acceptable carrier for these live bacteria.
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