Invention Grant
US08574881B2 Compositions useful for detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes
有权
用于检测或定量所需靶分子,新染料,复合染料和寡核苷酸的组合物或包含这些染料的多核苷酸
- Patent Title: Compositions useful for detection or quantification of desirable target molecules, novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes
- Patent Title (中): 用于检测或定量所需靶分子,新染料,复合染料和寡核苷酸的组合物或包含这些染料的多核苷酸
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Application No.: US12456513Application Date: 2009-06-17
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Publication No.: US08574881B2Publication Date: 2013-11-05
- Inventor: Praveen Pande , Yuejun Xiang , Elazar Rabbani
- Applicant: Praveen Pande , Yuejun Xiang , Elazar Rabbani
- Applicant Address: US NY Farmindale
- Assignee: Enzo Life Sciences, Inc.
- Current Assignee: Enzo Life Sciences, Inc.
- Current Assignee Address: US NY Farmindale
- Agent Anna D. DiGabriele Petti, Esq.
- Main IPC: C09B23/10
- IPC: C09B23/10

Abstract:
The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties.
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