Invention Grant
- Patent Title: Methods for augmentation collection of placental hematopoietic stem cells and uses thereof
- Patent Title (中): 胎盘造血干细胞增强收集方法及其用途
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Application No.: US13374105Application Date: 2011-12-12
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Publication No.: US08574899B2Publication Date: 2013-11-05
- Inventor: Vladimir B Serikov , Frans A Kuypers
- Applicant: Vladimir B Serikov , Frans A Kuypers
- Agency: Goodwin Procter LLP
- Main IPC: C12N5/00
- IPC: C12N5/00

Abstract:
The subject matter of this invention is a novel method to augment the process of obtaining populations of placental hematopoietic stem and progenitor cells for use in medical practices. A method of augmentation of stem cells collection from placenta is claimed comprising the steps of (a) infusing placental vessels cell preservation compound and a with a composition containing blockers of cell adhesion receptors, (b) incubating said placenta for a sufficient period of time, (c) placing placenta in a containment with sufficient intensity of electromagnetic or ultrasound field for a sufficient period of time; (d) eluting cell suspension from placental vessels, (e) collecting cell suspension and harvesting cells. Invention further claims a method of treatment a disease by means of administering therapeutic composition containing said placental-derived hematopoietic stem cells.
Public/Granted literature
- US20120177616A1 Methods for augmentation collection of placental hematopoietic stem cells and uses thereof Public/Granted day:2012-07-12
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