Invention Grant
- Patent Title: Method for expanding monocytes
- Patent Title (中): 扩增单核细胞的方法
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Application No.: US13359320Application Date: 2012-01-26
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Publication No.: US08574903B2Publication Date: 2013-11-05
- Inventor: Michael Sieweke
- Applicant: Michael Sieweke
- Applicant Address: FR Paris
- Assignee: Inserm (Institut Natuonal de la Santa et de la Recherche Medicale)
- Current Assignee: Inserm (Institut Natuonal de la Santa et de la Recherche Medicale)
- Current Assignee Address: FR Paris
- Agency: McAndrews, Held & Malloy Ltd.
- Priority: EP07300717 20070111
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02
Abstract:
The invention relates to an ex vivo method for expanding monocytes, macrophages or dendritic cells, which method comprises inhibiting the expression or the activity of MafB and c-Maf in monocytes, macrophages or dendritic cells; and expanding the cells in the presence of at least one cytokine or an agonist of cytokine receptor signaling.
Public/Granted literature
- US20120122207A1 Method for Expanding Monocytes Public/Granted day:2012-05-17
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