Invention Grant
- Patent Title: Peptides and methods for inhibiting G alpha protein signaling
- Patent Title (中): 肽和抑制Gα蛋白信号传导的方法
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Application No.: US13425922Application Date: 2012-03-21
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Publication No.: US08575103B2Publication Date: 2013-11-05
- Inventor: Guy Le Breton , Jin-Sheng Huang , Subhashini Srinivasan , Fadi T. Khasawneh
- Applicant: Guy Le Breton , Jin-Sheng Huang , Subhashini Srinivasan , Fadi T. Khasawneh
- Applicant Address: US IL Urbana
- Assignee: The Board of Trustees of the University of Illinois
- Current Assignee: The Board of Trustees of the University of Illinois
- Current Assignee Address: US IL Urbana
- Agency: Licata & Tyrrell, P.C.
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/08 ; C07K7/08 ; C07K7/06 ; C07K9/00 ; A61P7/02
Abstract:
Permeable Switch Region I and II peptides in the range of 9 to 25 amino acid residues in length are provided for specifically inhibiting signaling through Gα subunits. In addition, compositions and methods for inhibiting platelet aggregation and α11bβ3 integrin activation using the Switch Region I and II peptides are provided.
Public/Granted literature
- US20130040886A1 Peptides and Methods for Inhibiting G alpha Protein Signaling Public/Granted day:2013-02-14
Information query
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