Invention Grant
- Patent Title: Beta-lactamase inhibitory compounds
- Patent Title (中): β-内酰胺酶抑制化合物
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Application No.: US13629007Application Date: 2012-09-27
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Publication No.: US08575144B2Publication Date: 2013-11-05
- Inventor: John D. Buynak , Anjaneyulu Sheri , Sundar Ram Reddy Pagadala
- Applicant: Southern Methodist University
- Applicant Address: US TX Dallas
- Assignee: Southern Methodist University
- Current Assignee: Southern Methodist University
- Current Assignee Address: US TX Dallas
- Agency: Schwegman Lundberg & Woessner, P.A.
- Main IPC: A61K31/545
- IPC: A61K31/545 ; A61K31/546 ; C07D501/14
Abstract:
Inhibitors of the enzyme beta-lactamase are provided comprising compounds of formula (II) wherein R1 or R2 is a pyridyl group and R5 is a group of formula The compounds are adapted to inhibit beta-lactamase as produced by beta-lactam resistant bacterial strains. Methods of treatment of beta-lactam resistant bacterial infections in patients are provided.
Public/Granted literature
- US20130079318A1 BETA-LACTAMASE INHIBITORY COMPOUNDS Public/Granted day:2013-03-28
Information query
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