Invention Grant
- Patent Title: Triazole derivatives for treatment of Alzheimer's disease
- Patent Title (中): 用于治疗阿尔茨海默病的三唑衍生物
-
Application No.: US13139830Application Date: 2009-12-07
-
Publication No.: US08575150B2Publication Date: 2013-11-05
- Inventor: Christian Fischer , Joey Methot , Hua Zhou , Adam J. Schell , Benito Munoz , Alexey A. Rivkin , Sean P. Ahearn , Stephanie Chichetti , Rachel N. MacCoss , Sam Kattar , Matthew Christopher , Chaomin Li , Andrew Rosenau , William Colby Brown
- Applicant: Christian Fischer , Joey Methot , Hua Zhou , Adam J. Schell , Benito Munoz , Alexey A. Rivkin , Sean P. Ahearn , Stephanie Chichetti , Rachel N. MacCoss , Sam Kattar , Matthew Christopher , Chaomin Li , Andrew Rosenau , William Colby Brown
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Susan L. Hess; John C. Todaro
- International Application: PCT/US2009/066914 WO 20091207
- International Announcement: WO2010/071741 WO 20100624
- Main IPC: C07D249/14
- IPC: C07D249/14 ; A61K31/4196
Abstract:
According to the invention there is provided a compound of formula I or a pharmaceutically acceptable salt or hydrate thereof; wherein the variables are as defined herein. The compounds selectively attenuate the production of Aβ42 and hence are useful in treatment of Alzheimer's disease and related conditions.
Public/Granted literature
- US20120022044A1 TRIAZOLE DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE Public/Granted day:2012-01-26
Information query
