Invention Grant
- Patent Title: Imidazole derivatives as aldosterone synthase inhibitors
- Patent Title (中): 咪唑衍生物作为醛固酮合酶抑制剂
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Application No.: US13511581Application Date: 2010-11-29
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Publication No.: US08575160B2Publication Date: 2013-11-05
- Inventor: Robert Sun , Lauren G. Monovich , Sylvie Chamoin , John Westbrook
- Applicant: Robert Sun , Lauren G. Monovich , Sylvie Chamoin , John Westbrook
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Sophie Binet-Cross
- International Application: PCT/EP2010/068449 WO 20101129
- International Announcement: WO2011/064376 WO 20110603
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/4188 ; A61K31/428
Abstract:
The present invention provides a compound of formula (I) or pharmaceutically acceptable salt thereof, wherein the variables R1, R2, R3, R4, R5, R7 and p are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Public/Granted literature
- US20130065893A1 IMIDAZOLE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS Public/Granted day:2013-03-14
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