Invention Grant
- Patent Title: Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
- Patent Title (中): 嘌呤衍生物用于治疗过敏性，炎性和感染性疾病
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Application No.: US13058483Application Date: 2009-08-07
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Publication No.: US08575181B2Publication Date: 2013-11-05
- Inventor: Sebastien Andre Campos , Diane Mary Coe , Naimisha Trivedi
- Applicant: Sebastien Andre Campos , Diane Mary Coe , Naimisha Trivedi
- Applicant Address: US PA Philadelphia
- Assignee: GlaxoSmithKline LLC
- Current Assignee: GlaxoSmithKline LLC
- Current Assignee Address: US PA Philadelphia
- Agent Kathryn L. Coulter
- International Application: PCT/EP2009/060262 WO 20090807
- International Announcement: WO2010/018130 WO 20100218
- Main IPC: A61K31/52
- IPC: A61K31/52 ; C07D473/00
Abstract:
The present invention relates to compounds of formula (I): wherein R1 is C1-6alkylamino, or C1-6alkoxy; m is an integer having a value of 3, 4, or 5; n is an integer having a value of 0 to 3; p is an integer having a value of 1 or 2 and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
Public/Granted literature
- US20110135670A1 PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES Public/Granted day:2011-06-09
Information query
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