Invention Grant
US08575210B2 Use of indole derivatives as NURR-1 activators for treating parkinson's disease 有权
使用吲哚衍生物作为NURR-1激活剂治疗帕金森病

Use of indole derivatives as NURR-1 activators for treating parkinson's disease
Abstract:
The present invention relates to a compound derived from indole, especially a therapeutically useful compound, characterized in that it is selected from compounds of formula (I) in which R1 represents a halogen or a trifluoromethyl group, R2 represents a hydrogen atom or a C1-C4 alkyl group, R3 represents an isopropyl (1-methylethyl) group or a tert-butyl (1,1-dimethylethyl) group and n=3 or 4 and pharmaceutically acceptable salts of said compounds of formula (I). Application: Treatment of neurodegenerative diseases and more particularly of Parkinson's disease.
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