Invention Grant
- Patent Title: Hepatocyte growth factor (HGF) binding proteins
- Patent Title (中): 肝细胞生长因子（HGF）结合蛋白
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Application No.: US13589652Application Date: 2012-08-20
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Publication No.: US08575318B2Publication Date: 2013-11-05
- Inventor: May Han , S. Kirk Wright , William M. Winston, Jr. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
- Applicant: May Han , S. Kirk Wright , William M. Winston, Jr. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
- Applicant Address: US MA Cambridge
- Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Goodwin Procter LLP
- Main IPC: C07K16/24
- IPC: C07K16/24 ; C07K16/00
Abstract:
The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
Public/Granted literature
- US20130203970A1 HEPATOCYTE GROWTH FACTOR (HGF) BINDING PROTEINS Public/Granted day:2013-08-08
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