Invention Grant
- Patent Title: siRNA targeting kinase insert domain receptor (KDR)
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Application No.: US13524015Application Date: 2012-06-15
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Publication No.: US08575329B2Publication Date: 2013-11-05
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Thermo Fisher Scientific Biosciences Inc.
- Current Assignee: Thermo Fisher Scientific Biosciences Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Dorf & Nelson, LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12Q1/68
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for KDR.
Public/Granted literature
- US20120258889A1 siRNA Targeting Kinase Insert Domain Receptor (KDR) Public/Granted day:2012-10-11
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