Described herein are systems and methods for uniquely identifying, or “fingerprinting,” optical fibers based upon hi-resolution measurements of the backscattered light. One embodiment of the disclosure of this application is related to a computer readable storage medium including a set of instructions that are executable by a processor. The set of instructions being operable to retrieve a profile for an intended fiber, the profile including unique measurement data of the intended fiber, receive from an optical frequency-domain reflectometer further measurement data from a connected fiber within a network, compare the unique measurement data of the intended fiber to the further measurement data of the connected fiber, and confirm an identity of the connected fiber as being the intended fiber when the unique measurement data matches the further measurement data, and trigger an alert when the unique measurement data does not match the further measurement data.