A communication system for transmitting data, for example, within a System-in-Package. The system includes a first circuit configured for: a) dividing the data into a plurality of packets having a determined size; and b) creating for each of the packets a transmission segment including a segment header and the respective packet as payload. The system also includes a second circuit configured for: a) separating the transmission segments into a plurality of physical units, where the physical units have a determined size; and b) transmitting the physical units over a physical communication channel. In particular, the segment header includes at least one field that identifies the number of physical units that are to be transmitted.