Direct injection of a data to be transferred in a hybrid computing environment that includes a host computer and a plurality of accelerators, the host computer and the accelerators adapted to one another for data communications by a system level message passing module. Each accelerator includes a Power Processing Element (‘PPE’) and a plurality of Synergistic Processing Elements (‘SPEs’). Direct injection includes reserving, by each SPE, a slot in a shared memory region accessible by the host computer; loading, by each SPE into local memory of the SPE, a portion of data to be transferred to the host computer; executing, by each SPE in parallel, a data processing operation on the portion of the data loaded in local memory of each SPE; and writing, by each SPE, the processed data to the SPE's reserved slot in the shared memory region accessible by the host computer.