A portable power bank with card reading function includes a battery unit, a charging unit, a control unit, a voltage converting unit, a first card reading unit, and a connection interface unit. The battery unit is coupled with the charging unit and the voltage converting unit. The control unit is coupled with the charging unit, the voltage converting unit and the first card reading unit. The connection interface unit is coupled with the voltage converting unit and the control unit. The first card reading unit is configured for a first removable electronic card to insert thereinto. An electronic device is removably connected to the connection interface unit.