An optical receiver is described. This optical receiver has two operating modes: a calibration mode and a normal mode. During the normal mode, switches are used to electrically couple an input of a transimpedance amplifier (TIA) to an optical-to-electrical (OE) converter that receives an optical signal and provides a corresponding analog electrical signal. Moreover, during the calibration mode, the switches are used to electrically isolate the input of the TIA from the OE converter while maintaining a feedback path from an output of the TIA to the input of the TIA, thereby ensuring proper bias of the TIA during calibration. Furthermore, a frequency response of the TIA during the normal mode is substantially unchanged over an operating bandwidth of the TIA by the capability to electrically isolate the input of the TIA from the OE converter during the calibration mode.