A method for selecting a solvent or mixture of solvents useful for mitigating deposit formation, cleaning existing deposits, and/or decreasing the rate of deposit formation is disclosed. Decreasing the rate at which deposits may form and/or increasing the rate at which deposits may be removed can dramatically improve process economics (e.g., decreasing down time as a result of deposit formation). In one aspect, embodiments disclosed herein relate to a process for dispersing foulants in a hydrocarbon stream, including the steps of: determining a nature of foulants in a hydrocarbon stream; selecting a solvent or a mixture of solvents suitable to disperse the foulants based upon the determined nature; and contacting the foulants with the selected solvent or mixture of solvents.