Invention Grant
- Patent Title: Combinations for the treatment of diseases involving cell proliferation
- Patent Title (中): 用于治疗涉及细胞增殖的疾病的组合
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Application No.: US13342507Application Date: 2012-01-03
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Publication No.: US08591895B2Publication Date: 2013-11-26
- Inventor: Gerd Munzert , Martin Steegmaier , Anke Baum
- Applicant: Gerd Munzert , Martin Steegmaier , Anke Baum
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Anthony P. Bottino
- Priority: EP04019361 20040814; EP04019448 20040817
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K33/24 ; A61K31/535 ; A01N43/50 ; A01N43/00

Abstract:
Disclosed are pharmaceutical compositions for the treatment of diseases which involve cell proliferation. Also disclosed are methods for the treatment of said diseases, comprising co-administration of a compound 1 of Formula (I) wherein the groups L, R1, R2, R3, R4 and R5 have the meanings given herein and of an effective amount of an active compound 2 and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of a compound 1 of Formula (I) and of an effective amount of an active compound 2 and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.
Public/Granted literature
- US20120107312A1 Combinations for the Treatment of Diseases involving Cell Proliferation Public/Granted day:2012-05-03
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