Invention Grant
- Patent Title: Acetyl pyrrolidinyl indole derivative
- Patent Title (中): 乙酰基吡咯烷基吲哚衍生物
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Application No.: US13058626Application Date: 2009-08-03
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Publication No.: US08592428B2Publication Date: 2013-11-26
- Inventor: Hideaki Imamura , Takuya Suga , Hiroyuki Takahashi , Hideki Jona , Etsuko Hirose , Norikazu Ohtake
- Applicant: Hideaki Imamura , Takuya Suga , Hiroyuki Takahashi , Hideki Jona , Etsuko Hirose , Norikazu Ohtake
- Applicant Address: JP Tokyo
- Assignee: MSD K. K.
- Current Assignee: MSD K. K.
- Current Assignee Address: JP Tokyo
- Agent Anna L. Cocuzzo; Catherine D. Fitch
- Priority: JP2008-209153 20080815
- International Application: PCT/JP2009/064073 WO 20090803
- International Announcement: WO2010/018800 WO 20100218
- Main IPC: A61K31/497
- IPC: A61K31/497

Abstract:
The present invention relates to compounds, which are useful for treatment and/or prevention of diabetes mellitus, diabetes mellitus complications or obesity, since the compounds have glucokinase-activating effects, and are presented in Formula (I): wherein R1 represents a lower alkylsulfonyl group; R2 represents a hydrogen atom; R20 represents, e.g., a hydrogen atom; m represents an integer of from 1 to 3; and n represents zero or 1, or relates to a pharmaceutically acceptable salts thereof.
Public/Granted literature
- US20120108817A1 ACETYL PYRROLIDINYL INDOLE DERIVATIVE Public/Granted day:2012-05-03
Information query
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