Invention Grant
US08592643B2 Methods for introducing a human gene into a marmoset embryo for making a transgenic marmoset 有权
将人基因导入et et胚用于制备转基因m猴的方法

Methods for introducing a human gene into a marmoset embryo for making a transgenic marmoset
Abstract:
An object of the present invention is to provide a method for introducing a gene into an embryo for production of a human disease model primate animal using a non-human primate animal such as a marmoset. The present invention relates to a method for introducing a foreign gene into an early embryo of a non-human primate animal, which comprises placing early embryos of a non-human primate in a 0.2 M to 0.3 M sucrose solution, so as to increase the volume of the perivitelline spaces, and then injecting a viral vector containing a human foreign gene operably linked to a promoter into the perivitelline spaces of the early embryos.
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