A transmission method for use in a multi-hop wireless communication system is provided. The system includes a base station, a relay station and mobile stations. The method transmits using a downlink transmission frame that has a first zone for transmitting radio signals from the base station to the relay station, a second zone for transmitting radio signals from the relay station to a mobile station, and a third zone provided between the first zone and the second zone for transmitting radio signals from the base station directly to a mobile station.