A semi-persistent scheduling method is provided in the present disclosure, and the method comprises: when a semi-persistent scheduling periodicity comes, an evolved node B (eNB) and a terminal (UE) select a sub-frame in a sub-frame group as a sub-frame for current semi-persistent scheduling; the sub-frame group includes multiple sub-frames, and a sub-frame group periodicity equals to the semi-persistent scheduling periodicity. The problem that the sub-frames with the same relative position in different sub-frame groups are the sub-frames in which the collision between the initial transmission and the retransmission of the HARQ data packet most possibly occurs is considered by the technical solution of the present disclosure, so the purpose that prolonging the interval length of the collision between the initial transmission of the HARQ and the retransmission of the HARQ and reducing the collision between the initial transmission of the HARQ and the retransmission of the HARQ is achieved by reasonably configuring the number of sub-frames in a sub-frame group and alternately using different sub-frames in the sub-frame group.