An adaptive frequency hopping system and method uses two separate channel masks in an electronic device with collocated frequency hopping and single frequency systems to permit simultaneous transmissions by both systems without reducing a rate of data communication through the single frequency system. A first channel mask, corresponding to a transmission mask, and a second channel mask, corresponding to a reception mask, are separated from a carrier frequency used by the single frequency system, and optionally from two different carrier frequencies used by two different single frequency systems, by a selected magnitude of frequency difference. The selected magnitude of frequency difference may optionally be reduced to permit a channel mask to contain a minimum selected number of frequency hopping channels.