A method of selecting a modulation and coding scheme (MCS) index in a wireless communication system is disclosed. More specifically, the method includes measuring a frequency selectivity of a receiving channel, selecting a MCS index having a coding rate below a prescribed coding rate threshold value if the measured frequency selectivity is greater than or equal to a specified frequency selectivity threshold, and selecting the MCS index having the coding rate above or equal to the prescribed coding rate threshold value if the measured frequency selectivity is less than the specified frequency selectivity threshold.