The present invention provides novel fuel assemblies for use with PWR nuclear reactors and power plants, and in particular, VVER nuclear reactors. The fuel assemblies offer enhanced structural stability, skeletal rigidity, and distortion (bow and twist) resistance to support high burn-up fuel management. Each fuel assembly may include a plurality of fuel rods, a plurality of control rods and guide thimbles, at least one instrumentation tube, and a plurality of grids. At least one fuel rod is replaced with a structural support replacement rod made from zirconium (Zr) alloy, stainless steel, or any other suitable material. The structural support replacement rod may be hollow or solid. The structural support replacement rods are preferably disposed at or about the periphery, and in some cases, the corners of the geometric array, which is preferably a hexagon or square.