This disclosure describes systems and methods for monitoring ventilatory parameters, analyzing ventilatory data associated with those parameters, and providing useful notifications and/or recommendations to clinicians. For example, many clinicians may not easily identify or recognize data patterns and correlations indicative of a fluctuation in resistance during mechanical ventilation of a patient. Furthermore, clinicians may not easily determine potential causes for the fluctuation in resistance and/or steps for mitigating the fluctuation in resistance. According to embodiments, a ventilator may be configured to monitor and evaluate diverse ventilatory parameters to detect fluctuations in resistance and may issue suitable notifications and recommendations to the clinician based on potential causes of the fluctuation, ventilatory and/or patient data, etc. The suitable notifications and recommendations may further be provided in a hierarchical format such that the clinician may selectively access information regarding the fluctuation in resistance.