Invention Grant
US08597880B2 Methods and compositions for identifying increased risk of developing fragile X-associated disorders
有权
用于鉴定发展脆性X相关疾病的风险增加的方法和组合物
- Patent Title: Methods and compositions for identifying increased risk of developing fragile X-associated disorders
- Patent Title (中): 用于鉴定发展脆性X相关疾病的风险增加的方法和组合物
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Application No.: US12681433Application Date: 2008-10-02
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Publication No.: US08597880B2Publication Date: 2013-12-03
- Inventor: Stephen J. Tapscott , Galina N. Filippova , Paula D. Ladd
- Applicant: Stephen J. Tapscott , Galina N. Filippova , Paula D. Ladd
- Applicant Address: US WA Seattle
- Assignee: The Fred Hutchinson Cancer Research Center
- Current Assignee: The Fred Hutchinson Cancer Research Center
- Current Assignee Address: US WA Seattle
- Agency: Myers Bigel Sibley & Sajovec, PA
- International Application: PCT/US2008/011406 WO 20081002
- International Announcement: WO2009/045467 WO 20090409
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/02 ; C07H21/04
Abstract:
The present invention provides compositions and methods of identifying a subject as having an increased risk of developing fragile X-associated tremor and ataxia syndrome (FXTAS) or identifying a subject having an increased risk of developing fragile X syndrome (FXS), comprising analyzing messenger RNA (mRNA) transcripts and/or translation products of the antisense gene ASFMR1.
Public/Granted literature
- US20100279293A1 METHODS AND COMPOSITIONS FOR IDENTIFYING INCREASED RISK OF DEVELOPING FRAGILE X-ASSOCIATED DISORDERS Public/Granted day:2010-11-04
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