Invention Grant
- Patent Title: Mutant yeast strains capable of accumulating a large quantity of lipids
- Patent Title (中): 能够积聚大量脂质的突变酵母菌株
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Application No.: US13003757Application Date: 2009-07-08
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Publication No.: US08597931B2Publication Date: 2013-12-03
- Inventor: Jean-Marc Nicaud , Thierry Chardot , Athanasios Beopoulos
- Applicant: Jean-Marc Nicaud , Thierry Chardot , Athanasios Beopoulos
- Applicant Address: FR Paris FR Paris
- Assignee: Institut National de la Recherche Agronomique (INRA),Centre National de la Recherche Scientifique (CNRS)
- Current Assignee: Institut National de la Recherche Agronomique (INRA),Centre National de la Recherche Scientifique (CNRS)
- Current Assignee Address: FR Paris FR Paris
- Agency: Lathrop & Gage LLP
- Priority: FR0854786 20080711
- International Application: PCT/FR2009/000848 WO 20090708
- International Announcement: WO2010/004141 WO 20100114
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12P7/64
Abstract:
The subject of the present invention is a novel mutant yeast strain, particularly a Yarrowia lipolytica strain, capable of accumulate a large quantity of lipids. The said strain does not express the GUT2 gene. According to one variant, the invention relates to mutant yeast strains, particularly Yarrowia lipolytica strains, which do not express the GUT2 gene and which furthermore do not carry out the β-oxidation of lipids. Preferably, the mutant strains which do not express the GUT2 gene and which furthermore do not carry out β-oxidation of lipids do not express the POX 2 through POX 5 genes, most preferably the POX 1 through 6 genes. The subject of the invention is also a method for producing the strains according to the invention and the use of the said strains in the production of lipids.
Public/Granted literature
- US20110183387A1 New Mutant Yeast Strains Capable of Accumulating a Large Quantity of Lipids Public/Granted day:2011-07-28
Information query
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