Invention Grant
US08598124B2 Peptides derived from HMG-CoA reductase and cosmetic and/or pharmaceutical composition containing same
有权
衍生自HMG-CoA还原酶的肽和含有它们的化妆品和/或药物组合物
- Patent Title: Peptides derived from HMG-CoA reductase and cosmetic and/or pharmaceutical composition containing same
- Patent Title (中): 衍生自HMG-CoA还原酶的肽和含有它们的化妆品和/或药物组合物
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Application No.: US13141358Application Date: 2009-12-23
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Publication No.: US08598124B2Publication Date: 2013-12-03
- Inventor: Claude Dal Farra , Nouha Domloge , Jean-Marie Botto
- Applicant: Claude Dal Farra , Nouha Domloge , Jean-Marie Botto
- Applicant Address: US DE Wilmington
- Assignee: ISP Investments Inc.
- Current Assignee: ISP Investments Inc.
- Current Assignee Address: US DE Wilmington
- Agency: Thompson Hine L.L.P.
- Priority: FR0807364 20081223
- International Application: PCT/FR2009/001476 WO 20091223
- International Announcement: WO2010/072927 WO 20100701
- Main IPC: A61K8/64
- IPC: A61K8/64 ; A61K38/06 ; A61K38/07 ; A61K38/08 ; A61K9/00 ; C07K5/08 ; C07K5/10 ; C07K7/06
Abstract:
The present invention relates to peptides derived from human HMG-CoA reductase of general formula (I): R1-(AA)n-X1-Gly-Lys-X2-(AA)p-R2, And of sequence SEQ ID No. 1 to SEQ ID No. 10. The present invention also relates to a cosmetic or pharmaceutical composition comprising at least one peptide of general formula (I), in a physiologically suitable medium.The present invention further relates to the use of this novel peptide as an active principle that activates human HMG-CoA reductase in a cosmetic composition intended to strengthen the barrier function of the skin and to stimulate epidermal differentiation. The invention further applies to a cosmetic treatment method intended to prevent and/or combat the external stresses and signs of cutaneous aging.
Public/Granted literature
- US20110286991A1 PEPTIDES DERIVED FROM HMG-COA REDUCTASE AND COSMETIC AND/OR PHARMACEUTICAL COMPOSITION CONTAINING SAME Public/Granted day:2011-11-24
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