Invention Grant
- Patent Title: Ritonavir bis-hydrochloride
- Patent Title (中): 利托那韦双盐酸盐
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Application No.: US13328043Application Date: 2011-12-16
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Publication No.: US08598216B1Publication Date: 2013-12-03
- Inventor: Maurizio Acquasaliente , Didier Houllemare , Geoff Zhang , Pulla Singam , John Morris , Kennan Marsh , Martin Babcock , John Pavlina , Yi Shi , Yuchuan Gong
- Applicant: Maurizio Acquasaliente , Didier Houllemare , Geoff Zhang , Pulla Singam , John Morris , Kennan Marsh , Martin Babcock , John Pavlina , Yi Shi , Yuchuan Gong
- Applicant Address: US IL North Chicago
- Assignee: Abbvie Inc.
- Current Assignee: Abbvie Inc.
- Current Assignee Address: US IL North Chicago
- Agency: J.A. Lindeman & Co., PLLC
- Main IPC: A61K31/426
- IPC: A61K31/426 ; A61K31/41
Abstract:
The invention relates to ritonavir bis-hydrochloride, processes for the preparation of the ritonavir bis-hydrochloride, pharmaceutical compositions containing the ritonavir bis-hydrochloride and made from it, and methods of using the ritonavir bis-hydrochloride to inhibit HIV protease or enhance the pharmacokinetics of compounds which are metabolized by cytochrome P450 3A4.
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