Invention Grant
- Patent Title: Process for the preparation of atovaquone
- Patent Title (中): 制备阿托伐醌的方法
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Application No.: US13993683Application Date: 2011-12-13
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Publication No.: US08598387B2Publication Date: 2013-12-03
- Inventor: Andrew Neil Dwyer , Andrew Gordon , Michael Urquhart
- Applicant: Andrew Neil Dwyer , Andrew Gordon , Michael Urquhart
- Applicant Address: GB Brentford, Middlesex
- Assignee: Glaxo Group Limited
- Current Assignee: Glaxo Group Limited
- Current Assignee Address: GB Brentford, Middlesex
- Agent Bonnie L. Deppenbrock
- International Application: PCT/EP2011/072600 WO 20111213
- International Announcement: WO2012/080243 WO 20120621
- Main IPC: C07C49/603
- IPC: C07C49/603 ; C07C69/78 ; C07C45/42 ; C07D307/88 ; C07D311/76
Abstract:
Disclosed herein is novel process for preparation of atovaquone, which process includes reacting 1H-2-benzopyran-1,4(3H)-dione with 4-(4-chlorophenyl)cyclohexanecarbaldehyde. The invention further discloses novel intermediates useful in the preparation of atovaquone.
Public/Granted literature
- US20130267717A1 PROCESS FOR THE PREPARATION OF ATOVAQUONE Public/Granted day:2013-10-10
Information query
