A syringe protector. The syringe protector includes a clamping member, a guard member, and a retaining member. The clamping member being able to lockably engage the needle guard and allow the passage of a needle therethrough. Insertion of the clamping member into the guard member creates a locking interaction between the toothed surface of the clamping member and a complementary toothed or ribbed surface of the guard member. Further, the clamping member holds a retaining member which acts to secure a syringe body once the needle of the syringe enters the guard member.