User equipment reports periodically or aperiodically serving cell reference signal received power and quality as well as uplink power headroom information to the serving evolved NodeB (eNB). eNB calculates a current interference level experienced by the UE from the feedback report and its own loading. Since the self-interference is not flat across frequencies, the tolerable self-interference level depends on downlink scheduling. From the calculated interference, eNB can calculate uplink allocation parameters. Sequence of scheduling decisions can be downlink allocation, determining tolerable self-interference, and uplink allocation, or in the opposite order, or the downlink and uplink allocation can be jointly determined using the available. An additional scheduling constraint can be derived for meeting the co-existence requirements, which can be determined from the power headroom report alone. Thereby interference to other user equipment or self-interference (self-desensitization) is addressed when inadequate attenuation exists while also allowing deploying full system bandwidth.