Apparatus and methods for use in an image-guided interventional procedure are described herein. In one embodiment, an apparatus includes a base configured to be releasably coupled to a patient's skin. A support portion extends from the base at an angle transverse to a longitudinal axis defined by the base. The support portion has a first end portion and a second end portion. The first end portion is disposed adjacent the base. A holder portion extends from the second end portion of the support portion. The holder portion defines an opening and is configured to be moved between a first configuration in which the opening defined by the holder portion has a first size and is configured to movably receive an interventional tool therethrough, and a second configuration in which the opening defined by the holder portion has a second size different than the first size.