Invention Grant
- Patent Title: Cellular and viral inactivation
- Patent Title (中): 细胞和病毒灭活
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Application No.: US12847231Application Date: 2010-07-30
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Publication No.: US08613934B2Publication Date: 2013-12-24
- Inventor: Yossef Raviv , Julie M. Belanger , Mathias Viard , Robert Blumenthal , Julian W. Bess, Jr.
- Applicant: Yossef Raviv , Julie M. Belanger , Mathias Viard , Robert Blumenthal , Julian W. Bess, Jr.
- Applicant Address: US DC Washington
- Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Woodcock Washburn LLP
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C12N7/06 ; C12N13/00 ; A61P31/12 ; A61P37/04
Abstract:
The invention involves inactivation of viral populations by treating the viral populations with a compound to crosslink proteins in the viral membrane, UV irradiation and further inactivation of the viruses using detergent(s). According to the invention, this method preserves the native structure of viral epitopes so that the inactivated viral preparations can be used in immunological compositions that will inhibit and/or prevent viral infection when administered to an animal.
Public/Granted literature
- US20110038890A1 Cellular And Viral Inactivation Public/Granted day:2011-02-17
Information query
