Invention Grant
- Patent Title: Cancer imaging and treatment
- Patent Title (中): 癌症成像和治疗
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Application No.: US12675151Application Date: 2008-09-01
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Publication No.: US08614290B2Publication Date: 2013-12-24
- Inventor: Hans Jürgen Wester , Horst Kessler , Oliver Demmer , Ingrid Dijkgraaf
- Applicant: Hans Jürgen Wester , Horst Kessler , Oliver Demmer , Ingrid Dijkgraaf
- Applicant Address: DE Munich
- Assignee: Technische Universitat Munchen
- Current Assignee: Technische Universitat Munchen
- Current Assignee Address: DE Munich
- Priority: GB0716897.4 20070830
- International Application: PCT/GB2008/002950 WO 20080901
- International Announcement: WO2009/027706 WO 20090305
- Main IPC: G01N33/567
- IPC: G01N33/567 ; C07K7/64

Abstract:
A compound, or a pharmaceutically acceptable salt or ester thereof, comprises the structure: [(P1-S1j)p-L-(S2q-P2)r]t wherein: P1 and P2, which may be the same or different, are cyclic oligopeptide moieties, at least one of P1 and P2 having the motif B-Arg or B-(Me) Arg within the cyclic moiety, wherein B is a basic amino acid, a derivative thereof, or phenylalanine or a derivative thereof; S1 and S2 are spacer groups, which may be the same or different; L is a linker moiety containing at least two functional groups for attachment of the cyclic oligopeptides or spacer groups; n and q are independently 0 or 1; p and r are independently integers of 1 or more; and t is an integer of 1 or more, provided that, when t, p or r is greater than 1, the cyclic oligopeptide moiety, spacer group and/or the value of j or q may be the same or different between the multiple (P1-S1j) moieties or multiple (S2q-P2) moieties.
Public/Granted literature
- US20100240072A1 Cancer Imaging and Treatment Public/Granted day:2010-09-23
Information query
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