Invention Grant
US08614330B2 Substituted benz-azoles and methods of their use as inhibitors of RAF kinase
失效
取代的苯并唑及其作为RAF激酶抑制剂的方法
- Patent Title: Substituted benz-azoles and methods of their use as inhibitors of RAF kinase
- Patent Title (中): 取代的苯并唑及其作为RAF激酶抑制剂的方法
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Application No.: US12723483Application Date: 2010-03-12
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Publication No.: US08614330B2Publication Date: 2013-12-24
- Inventor: Payman Amiri , Wendy Fantl , Teresa Hansen , Barry Haskell Levine , Christopher McBride , Daniel J. Poon , Savithri Ramurthy , Paul A. Renhowe , Cynthia M. Shafer , Sharadha Subramanian , Leonard Sung
- Applicant: Payman Amiri , Wendy Fantl , Teresa Hansen , Barry Haskell Levine , Christopher McBride , Daniel J. Poon , Savithri Ramurthy , Paul A. Renhowe , Cynthia M. Shafer , Sharadha Subramanian , Leonard Sung
- Applicant Address: US CA Emeryville
- Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee Address: US CA Emeryville
- Agency: Christensen O'Connor Johnson Kindness PLLC
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; C07D417/12
Abstract:
New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
Public/Granted literature
- US20100196368A1 SUBSTITUTED BENZ-AZOLES AND METHODS OF THEIR USE AS INHIBITORS OF RAF KINASE Public/Granted day:2010-08-05
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