The subject matter described herein includes methods, systems, and computer readable media for detecting and mitigating fraud in a distributed monitoring system which includes fixed-location monitoring and communication devices. According to one aspect, a method for detecting and mitigating fraud includes receiving a signaling message that originates or appears to originate from a wireless communication device that is associated with a fixed-location management system that performs at least one of monitoring and control of a resource, wherein the wireless communication device is responsible for communicating information generated by the management system over a network. The method further includes determining whether the signaling message indicates an expected location of the wireless communication device and in response to a determination that the signaling message does not indicate an expected location of the wireless communication device, initiating a mitigating action.