Methods and systems for prognostic condition assessment decision aid of a fleet of vehicles are disclosed. In one embodiment, a method includes providing a schedule of missions and maintenance of a fleet of vehicles, comprising receiving data from the fleet of vehicles for missions and maintenance activity, determining mission and maintenance requirements, processing the received data and requirements to provide an operational allocation of the fleet of vehicles, determining an alternative allocation of the operational allocation of the fleet of vehicles, the alternative allocation satisfying at least one operational objective for the fleet of vehicles, and generating a schedule for the alternative allocation of the fleet of vehicles.