Invention Grant
- Patent Title: Antigenic GM-CSF peptides and antibodies to GM-CSF
- Patent Title (中): 抗原GM-CSF肽和GM-CSF抗体
-
Application No.: US13659165Application Date: 2012-10-24
-
Publication No.: US08623364B2Publication Date: 2014-01-07
- Inventor: Philip M. Sass , Nicholas C. Nicolaides , Luigi Grasso , Jian Li , Qimin Chao , Eric Routhier , Wolfgang Ebel
- Applicant: Philip M. Sass , Nicholas C. Nicolaides , Luigi Grasso , Jian Li , Qimin Chao , Eric Routhier , Wolfgang Ebel
- Applicant Address: US PA Exton
- Assignee: Morphotek, Inc.
- Current Assignee: Morphotek, Inc.
- Current Assignee Address: US PA Exton
- Agency: Woodcock Washburn, LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/00 ; C07K16/22 ; C12P21/08
Abstract:
Hybridoma lines that secrete human monoclonal antibodies with high binding specificity and biological activity, particularly neutralizing activity against granulocyte-macrophage colony stimulating factor, and methods of generating the hybridoma lines are provided. Target antigens and epitopes are also provided. The antibodies may be used in therapeutic methods, for example in the treatment of cancer, infectious disease, or autoimmune disease.
Public/Granted literature
- US20130058945A1 Antigenic GM-CSF Peptides and Antibodies to GM-CSF Public/Granted day:2013-03-07
Information query
