Invention Grant
- Patent Title: Aβ binding molecules
- Patent Title (中): Abeta结合分子
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Application No.: US13332753Application Date: 2011-12-21
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Publication No.: US08623365B2Publication Date: 2014-01-07
- Inventor: Julian Davies , Ying Tang , Jeffry Dean Watkins
- Applicant: Julian Davies , Ying Tang , Jeffry Dean Watkins
- Applicant Address: US IN Indianapolis
- Assignee: Applied Molecular Evolution, Inc.
- Current Assignee: Applied Molecular Evolution, Inc.
- Current Assignee Address: US IN Indianapolis
- Agent Sanjay Jivraj
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
The present invention encompasses isolated antibodies, or fragments thereof, that are humanized variants of murine antibody 266 which employ complementarity determining regions derived from murine antibody 266. The variant antibodies are useful for treatment or prevention of conditions and diseases associated with Aβ, including Alzheimer's disease, Down's syndrome, cerebral amyloid angiopathy, mild cognitive impairment, and the like.
Public/Granted literature
- US20120114560A1 ABETA BINDING MOLECULES Public/Granted day:2012-05-10
Information query
