Invention Grant
US08623378B2 Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
有权
糖缀合物,糖氨基酸,其中间体及其用途
- Patent Title: Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
- Patent Title (中): 糖缀合物,糖氨基酸,其中间体及其用途
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Application No.: US13018249Application Date: 2011-01-31
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Publication No.: US08623378B2Publication Date: 2014-01-07
- Inventor: Samuel J. Danishefsky , Jennifer R. Allen , Govindaswami Ragupathi , Philip O. Livingston , Lawrence Williams
- Applicant: Samuel J. Danishefsky , Jennifer R. Allen , Govindaswami Ragupathi , Philip O. Livingston , Lawrence Williams
- Applicant Address: US NY New York
- Assignee: Sloan-Kettering Institute for Cancer Research
- Current Assignee: Sloan-Kettering Institute for Cancer Research
- Current Assignee Address: US NY New York
- Agency: Choate, Hall & Stewart, LLP
- Agent Brenda Herschbach Jarrell; John P. Rearick
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K39/385 ; A61K31/70 ; A61K31/715

Abstract:
The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.
Public/Granted literature
- US20110206757A1 NOVEL GLYCOCONJUGATES, GLYCOAMINO ACIDS, INTERMEDIATES THERETO, AND USES THEREOF Public/Granted day:2011-08-25
Information query
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