Invention Grant
US08623381B2 Viral strains derived from the vaccinia virus Lister VACV-107 and uses thereof
有权
来自痘苗病毒Lister VACV-107的病毒株及其用途
- Patent Title: Viral strains derived from the vaccinia virus Lister VACV-107 and uses thereof
- Patent Title (中): 来自痘苗病毒Lister VACV-107的病毒株及其用途
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Application No.: US13119812Application Date: 2009-09-18
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Publication No.: US08623381B2Publication Date: 2014-01-07
- Inventor: Jean-marc Crance , Daniel Garin , Daniele Gratier , Anne-Laure Favier , Robert Drillien , Matthias Hebben , Daniele Spehner , Karine Pradeau
- Applicant: Jean-marc Crance , Daniel Garin , Daniele Gratier , Anne-Laure Favier , Robert Drillien , Matthias Hebben , Daniele Spehner , Karine Pradeau
- Applicant Address: FR Paris
- Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee Address: FR Paris
- Agency: Whitham, Curtis, Christofferson & Cook, PC
- Priority: EP08305570 20080919
- International Application: PCT/EP2009/062114 WO 20090918
- International Announcement: WO2010/031837 WO 20100325
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K39/275
Abstract:
The present invention relates to viral strains derived from the vaccinia virus Lister VACV-107 and to pharmaceutical composition containing the viral strains. More particularly, the present invention relates to a viral strain derived from the vaccinia virus Lister VACV-107 wherein strain contains in its genomic sequence (SEQ ID N°1) at least one deletion selected from the group consisting of: deletion of the nucleotides 19758 to 28309 in the sequence ID NO°1 (Δ18), deletion of the nucleotides 161293 to 164811 in the sequence ID NO°1 (Δ20), deletion of the nucleotides 181231 to 183304 in the sequence ID NO°1 (Δ21), deletion of the nucleotides 6118 to 9677 in the sequence ID NO°1 (Δ22), deletion of the nucleotides 1833 to 3574 and 185848 to 187589 in the sequence ID NO°1 (Δ23).
Public/Granted literature
- US20110171256A1 VIRAL STRAINS DERIVED FROM THE VACCINIA VIRUS LISTER VACV-107 AND USES THEREOF Public/Granted day:2011-07-14
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