Invention Grant
US08623405B2 Finely divided composition containing poorly water soluble substance
有权
精细分散的组合物含有水溶性差的物质
- Patent Title: Finely divided composition containing poorly water soluble substance
- Patent Title (中): 精细分散的组合物含有水溶性差的物质
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Application No.: US11795734Application Date: 2006-01-27
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Publication No.: US08623405B2Publication Date: 2014-01-07
- Inventor: Hiroshi Suzuki , Tomohiro Yoshinari , Naomi Nagaoka
- Applicant: Hiroshi Suzuki , Tomohiro Yoshinari , Naomi Nagaoka
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: JP2005-022124 20050128
- International Application: PCT/JP2006/301816 WO 20060127
- International Announcement: WO2006/087919 WO 20060824
- Main IPC: A61K9/48
- IPC: A61K9/48 ; A61K9/20 ; A61K47/30 ; A61K9/28 ; A61K9/14
Abstract:
The disclosed method involves preparation of a composition containing a poorly water soluble substance. The composition has a median diameter of not more than 1 μm, and includes (i) a poorly water soluble substance, (ii) polyvinylpyrrolidone or a vinylpyrrolidone-vinyl acetate copolymer, and (iii) an auxiliary dispersion stabilizer. By employing such constitution, a poorly water soluble substance is sufficiently micronized and a composition containing a poorly water soluble substance showing good absorbability of the poorly water soluble substance can be provided.
Public/Granted literature
- US20080118552A1 Finely Divided Composition Containing Poorly Water Soluble Substance Public/Granted day:2008-05-22
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