Invention Grant
- Patent Title: Process for producing L-amino acid
- Patent Title (中): 生产L-氨基酸的方法
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Application No.: US13148564Application Date: 2010-02-09
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Publication No.: US08623619B2Publication Date: 2014-01-07
- Inventor: Kazuhiko Tabata , Akihiro Senoo
- Applicant: Kazuhiko Tabata , Akihiro Senoo
- Applicant Address: JP Tokyo
- Assignee: Kyowa Hakko Bio Co., Ltd.
- Current Assignee: Kyowa Hakko Bio Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Leydigs, Voit & Mayer, Ltd.
- Priority: JP2009-027881 20090209
- International Application: PCT/JP2010/051886 WO 20100209
- International Announcement: WO2010/090330 WO 20100812
- Main IPC: C12P13/04
- IPC: C12P13/04 ; C12P13/22 ; C12N9/00 ; C12N1/20 ; C12N15/00 ; C07H21/04

Abstract:
The present invention provides a method of improving efficiency of a fermentative production of an L-amino acid. To be specific, the present invention provides a process for producing a L-amino acid, comprising culturing a microorganism wherein the activity of the protein described in any one of (1) to (3) below is higher than that of the parent strain in a medium to produce the L-amino acid and accumulate the L-amino acid in the medium, and then collecting the L-amino acid from the medium: (1) a protein comprising the amino acid sequence shown by any one of SEQ ID NOS:2, 4, 6 and 8 (2) a protein consisting of the amino acid sequence resulting from deletion, substitution or addition of one or more amino acids in the amino acid sequence shown in any one of SEQ ID NOS:2, 4, 6 and 8, and having L-amino acid transport activity (3) a protein consisting of the amino acid sequence having 80% or more homology to the amino acid sequence shown in any one of SEQ ID NOS:2, 4, 6 and 8, and having L-amino acid transport activity.
Public/Granted literature
- US20120015409A1 PROCESS FOR PRODUCING L-AMINO ACID Public/Granted day:2012-01-19
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