Invention Grant
- Patent Title: Modified secretion system to increase expression of polypeptides in bacteria
- Patent Title (中): 改良的分泌系统以增加细菌中多肽的表达
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Application No.: US13652107Application Date: 2012-10-15
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Publication No.: US08623630B2Publication Date: 2014-01-07
- Inventor: Anita Van Kimmenade , Carol Fioresi , Caroline Peres , Eugenio Ferrari
- Applicant: Danisco US Inc.
- Applicant Address: US CA Palo Alto
- Assignee: Danisco US Inc.
- Current Assignee: Danisco US Inc.
- Current Assignee Address: US CA Palo Alto
- Agency: Danisco US Inc.
- Main IPC: C12N15/75
- IPC: C12N15/75 ; C12N9/52 ; C12N1/20 ; C12N15/63
Abstract:
The present invention provides methods of altering the production of desired polypeptides in a host cell. In particular, the present invention provides polynucleotides encoding truncated SecG proteins capable of facilitating the secretion of desired proteases by a bacterial host cell, such as Bacillus species, as well as expression vectors and a host cell containing the polynucleotides.
Public/Granted literature
- US20130102052A1 MODIFIED SECRETION SYSTEM TO INCREASE EXPRESSION OF POLYPEPTIDES IN BACTERIA Public/Granted day:2013-04-25
Information query
IPC分类:
